Scientific specifics (Chemical, physicochemical and pharmaceutical analyzes, study of the rheological behavior of biomaterials by rheology. Spectroscopic analysis (UV / Visible, Fluorescence, NIRS). Chromatographic analyzes (UHPLC, HPLC with DAD or CAD detection): impurity profile, assay, stability Rheology analyzes: viscosity, linear visco-elasticity domain, elastic / viscous moduli, thixotropy, sol-gel, etc. Development of methods and validation according to ICH international pharmaceutical standards. Accelerated stability study. Development by QbD