Publications

Gaubert A, Castagnet T, Marsh J, Barthélémy P. Fluorinated GlycoNucleoLipid-based hydrogels as new spatiotemporal stimulable DDS. Drug Deliv Transl Res., (2024) doi: 10.1007/s13346-024-01550-9. Epub ahead of print. PMID: 38388815.

J. Carvalho, J. Lopes-Nunes, B. Vialet, T. Rosado, E. Gallardo, J. Vale, C. Eloy, S. Ferreira, R. Palmeira-de-Oliveira, MP Cabral Campello, A.P., P. Barthélémy, J.-L. Mergny, G. F. Salgado, J. A. Queiroz, A. D. Ellington, C. Cruz. Nanoaggregate-forming lipid-conjugated AS1411 aptamer as a promising tumor-targeted delivery system ofanticancer agents. Nanomedicine: NBM, (2021) ; 36:102429, https://doi.org/10.1016/j.nano.2021.102429

Kauss, T.; Arpin, C.; Bientz, L.; Vinh Nguyen, P.; Vialet, B.; Benizri, S.; Barthélémy, P. Lipid Oligonucleotides as a New Strategy for Tackling the Antibiotic Resistance. Sci Rep 2020, 10 (1), 1054. https://doi.org/10.1038/s41598-020-58047-x

Baillet, J.; Gaubert, A.; Bassani, D.; Verget, J.; Latxague, L.; Barthelemy, P. Supramolecular Gels Derived from Nucleoside Based Bolaamphiphiles as a Light-Sensitive Soft Material. Chem. Commun. 2020, 10.1039.D0CC00336K. https://doi.org/10.1039/D0CC00336K

Dessane, B.; Smirani, R.; Bouguéon, G.; Kauss, T.; Ribot, E.; Devillard, R.; Barthélémy, P.; Naveau, A.; Crauste-Manciet, S. Nucleotide Lipid-Based Hydrogel as a New Biomaterial Ink for Biofabrication. Sci Rep 2020, 10 (1), 2850. https://doi.org/10.1038/s41598-020-59632-w

Cunha, A.; Prévot, G.; Mousli, Y.; Barthélémy, P.; Crauste-Manciet, S.; Dehay, B.;  Desvergnes, V. Synthesis and Intracellular Uptake of Rhodamine–Nucleolipid Conjugates into a Nanoemulsion Vehicle. ACS Omega 2020 5 (11), 5815-5823 DOI: 10.1021/acsomega.9b03992

Giraud, J.; Molina‐Castro, S.; Seeneevassen, L.; Sifré, E.; Izotte, J.; Tiffon, C.; Staedel, C.; Boeuf, H.; Fernandez, S.; Barthelemy, P.; Megraud, F.; Lehours, P.; Dubus, P.; Varon, C. Verteporfin Targeting YAP1/TAZ‐TEAD Transcriptional Activity Inhibits the Tumorigenic Properties of Gastric Cancer Stem Cells. Int. J. Cancer 2020, 146 (8), 2255–2267. https://doi.org/10.1002/ijc.32667

Debiais, M.: Hamoud, A.;  Drain, R.;  Barthélémy, P. and  Desvergnes, V.  Bio-inspired NHC-organocatalyzed Stetter reaction
in aqueous conditions. RSC Adv., 2020, 10, 40709–40718. DOI: 10.1039/D0RA08326G

Bouguéon G., Kauss T., Dessane B., Barthélémy P., Crauste-Manciet S. Micro- and nano-formulations for bioprinting and additive manufacturing, Drug Discovery Today 2019,24(1):163-178. doi: 10.1016/j.drudis.2018.10.013

Benizri, S.; Gissot, A.; Martin, A.; Vialet, B.; Grinstaff, M. W.; Barthélémy, P. (2019) Bioconjugated Oligonucleotides: Recent Developments and Therapeutic Applications. Bioconj. Chem., doi: 10.1021/acs.bioconjchem.8b00761.

Clément, Y.; Gaubert, A.; Bonhommé, A.; Marote, P.; Mungroo, A.; Paillard, M.; Lantéri, P.; Morell, C. Raman Spectroscopy Combined with Advanced Chemometric Methods: A New Approach for Detergent Deformulation. Talanta 2019, 195, 441–446. https://doi.org/10.1016/j.talanta.2018.11.064

Deljehier, T.; Bouguéon, G.; Heloury, J.; Moreno, V.; Berroneau, A.; Crauste-Manciet, S. Simulation Program of a Cytotoxic Compounding Robot for Monoclonal Antibodies and Anti-Infectious Sterile Drug Preparation. J Oncol Pharm Pract 2019, 25 (8), 1873–1890. https://doi.org/10.1177/1078155218823911

Heloury, J.; Bouguéon, G.; Deljehier, T.; Jourand, A.; Berroneau, A.; Crauste-Manciet, S. Automation of Aseptic Sterile Preparation: Risk Analysis and Productivity Comparison with Manual Process. Pharmaceutical Technology in Hospital Pharmacy 2019, 4 (1), 15–28. https://doi.org/10.1515/pthp-2019-0001

Kauss, T.; Langlois, M.-H.; Guyonnet-Dupérat, A.; Phoeung, T.; Xie, X. Y.; Cartwright, A.; White, N.; Gomes, M.; Gaudin, K. Development of Rectodispersible Tablets and Granulate Capsules for the Treatment of Serious Neonatal Sepsis in Developing Countries. Journal of Pharmaceutical Sciences 2019, 108 (8), 2805–2813. https://doi.org/10.1016/j.xphs.2019.03.004

Mbarek, A.; Moussa, G.; Leblond Chain, J. Pharmaceutical Applications of Molecular Tweezers, Clefts and Clips. Molecules 2019, 24 (9), 1803. https://doi.org/10.3390/molecules24091803

Swastika; Chaturvedi, S.; Kaul, A.; Hazari, P. P.; Jha, P.; Pal, S.; Lal, S.; Singh, B.; Barthélémy, P.; Mishra, A. K. Evaluation of BBB Permeable Nucleolipid (NLDPU): A Di-C15-Ketalised Palmitone Appended Uridine as Neuro-Tracer for SPECT. International Journal of Pharmaceutics 2019, 565, 269–282. https://doi.org/10.1016/j.ijpharm.2019.04.074

Kowouvi K.; Alies B.; Gendrot M.; Gaubert A.; Vacher G.; Gaudin K.; Mosnier J.; Pradines B.; Barthelemy P.; Grislain L.; Millet P. (2019) Nucleoside-lipid-based nanocarriers for methylene blue delivery: potential application as anti-malarial drug. RSC Advances. doi: 10.1039/c9ra02576f.

Guthertz, A.; Lusseau, J.; Desvergnes, V.; Massip, S.; Landais, Y. (2019) An Approach toward the Synthesis of the Spiroimine Fragment of 13-Desmethylspirolide C and Gymnodimine A. Chem. Eur. J. doi: 10.1002/chem.201804972.

Bouguéon G, Kauss T, Dessane B, Barthélémy P, Crauste-Manciet S. (2019) Micro- and nano-formulations for bioprinting and additive. Drug Discov Today doi: 10.1016/j.drudis.2018.10.013.

Prévot G., Soria F.N., Thiolat M.-L., Daniel J., Verlhac J.B., Blanchard-Desce M., Bezard E., Barthélémy P., Crauste-Manciet S., Dehay B. Harnessing Lysosomal pH through PLGA Nanoemulsion as a Treatment of Lysosomal-Related Neurodegenerative Diseases. Bioconjugate Chemistry, 2018, 29(12):4083-4089.doi:10.1021/acs.bioconjchem.8b00697

Alies B, Ouelhazi M, Noireau A, Gaudin K, and Barthélémy P. (2018) Silver ions detection via nucleolipids self-assembly. Anal. Chem., DOI: 10.1021/acs.analchem.8b04066.

Kauss, T.; Gaubert, A.; Tabaran, L.; Tonelli, G.; Phoeung, T.; Langlois, M.-H.; White, N.; Cartwright, A.; Gomes, M.; Gaudin, K. Development of Rectal Self-Emulsifying Suspension of a Moisture-Labile Water-Soluble Drug. International Journal of Pharmaceutics 2018, 536 (1), 283–291. https://doi.org/10.1016/j.ijpharm.2017.11.067

Maisani, M.; Ziane, S.; Ehret, C.; Levesque, L.; Siadous, R.; Le Meins, J.-F.; Chevallier, P.; Barthélémy, P.; De Oliveira, H.; Amédée, J.; Mantovani, D.; Chassande, O. A New Composite Hydrogel Combining the Biological Properties of Collagen with the Mechanical Properties of a Supramolecular Scaffold for Bone Tissue Engineering. Journal of Tissue Engineering and Regenerative Medicine 2018, 12 (3), e1489–e1500. https://doi.org/10.1002/term.2569

Prata, C. A. H.; Luman, N. R.; Li, Y.; Luo, D.; McIntosh, T. J.; Barthélémy, P.; Grinstaff, M. W. Synthesis of Cationic Amphiphilic Surface-Block Polyester Dendrimers. Journal of Inorganic and Organometallic Polymers and Materials 2018, 28 (2), 383–398. https://doi.org/10.1007/s10904-017-0651-4

Prévot, G.; Soria, F. N.; Thiolat, M.-L.; Daniel, J.; Verlhac, J. B.; Blanchard-Desce, M.; Bezard, E.; Barthélémy, P.; Crauste-Manciet, S.; Dehay, B. Harnessing Lysosomal PH through PLGA Nanoemulsion as a Treatment of Lysosomal-Related Neurodegenerative Diseases. Bioconjugate Chemistry 2018, 29 (12), 4083–4089. https://doi.org/10.1021/acs.bioconjchem.8b00697

Verdun-Esquer, C.; Videau, N.; Partarrieu, I.; Atge, B.; Folch, C.; Gautier, Y.; Marty, S.; Crauste-Manciet, S.; Jourand, A.; Canal-Raffin, M. Mise en œuvre de mesures de prévention des expositions aux médicaments anticancéreux du personnel du CHU de Bordeaux. Archives des Maladies Professionnelles et de l’Environnement 2018, 79 (3), 391–392. https://doi.org/10.1016/j.admp.2018.03.396

Yabré, M.; Ferey, L.; Somé, I.; Gaudin, K. Greening Reversed-Phase Liquid Chromatography Methods Using Alternative Solvents for Pharmaceutical Analysis. Molecules 2018, 23 (5), 1065. https://doi.org/10.3390/molecules23051065

Gaubert, A;  Latxague, L;  Barthélémy, P. Nucleoside Lipid–Based Soft Materials. In Templated DNA Nanotechnology; Govindaraju, T., Ed.; Jenny Stanford Publishing, 2019; pp 149–176. https://doi.org/10.1201/9780429428661-5

Ferey, L.; Raimbault, A.; Rivals, I.; Gaudin, K. UHPLC Method for Multiproduct Pharmaceutical Analysis by Quality-by-Design. Journal of Pharmaceutical and Biomedical Analysis 2018, 148, 361–368

Ba, B.; Gaudin, K.; Désiré, A.; Phoeung, T.; Langlois, M.-H.; Behl, C. R.; Unowsky, J.; Patel, I. H.; Malick, A. W.; Gomes, M.; White, N.; Kauss, T. Ceftriaxone Absorption Enhancement for Noninvasive Administration as an Alternative to Injectable Solutions. Antimicrob Agents Chemother 2018, 62 (12), e01170-18, /aac/62/12/e01170-18.atom. https://doi.org/10.1128/AAC.01170-18

Ferey L, Slabi SA, Roy CE, Barthélémy P, Gaudin K. (2018) Chromatographic study of nucleoside-lipids by RP-UHPLC-DAD/CAD.
Anal Bioanal Chem. doi: 10.1007/s00216-018-1388-9.

Alies B., Ouelhazi MA1, Patwa A., Verget J., Navailles L., Desvergnes V., Barthélémy P. (2018) Cytidine- and guanosine-based nucleotide-lipids. Org Biomol Chem. DOI: 10.1039/c8ob01023d.

Baillet, J., Desvergnes, V., Hamoud, A., Latxague, L., Barthélémy, P. (2018) Lipid and Nucleic Acid Chemistries: Combining the Best of Both Worlds to Construct Advanced Biomaterials. Advanced  Materials; 30, 1705078. DOI: 10.1002/adma.201705078

Hamoud, A., Barthélémy, P. Desvergnes, V.  (2018) Organocatalyzed Stetter reaction as a bio-inspired tool for the synthesis of nucleic acids-based bioconjugates. Org Biomol Chem., DOI: 10.1039/C8OB00192H

Latxague, L., Gaubert, A., Barthélémy, P. (2018) Recent advances in the chemistry of glycoconjugate amphiphiles. Molecules, 23, 89; 1-25. doi:10.3390/molecules23010089

Benizri, S., Ferey, L., Alies, B., Mebarek N., Vacher, G., Appavoo, A., Gaudin, K., Barthélémy, P. (2018) Nucleoside-Lipid-Based Nanocarriers for Sorafenib Delivery. Nanoscale Research Letters. DOI 10.1186/s11671-017-2420-2

B. Vialet, A. Gissot, R. Delzor and P. Barthelemy, (2017), “Controlling G-quadruplex formation via lipid modification of oligonucleotide séquences” Chem. Commun., DOI: 10.1039/C7CC05693A.

Prévot, G.; Mornet, S.; Lorenzato, C.; Kauss, T.; Adumeau, L.; Gaubert, A.; Baillet, J.; Barthélémy, P.; Clofent-Sanchez, G.; Crauste-Manciet, S. Data on Iron Oxide Core Oil-in-Water Nanoemulsions for Atherosclerosis Imaging. Data in Brief 2017, 15, 876–881. https://doi.org/10.1016/j.dib.2017.10.059

Prévot, G.; Duonor-Cérutti, M.; Larivière, M.; Laroche-Traineau, J.; Jacobin-Valat, M. J.; Barthélémy, P.; Clofent-Sanchez, G.; Crauste-Manciet, S. Data on Atherosclerosis Specific Antibody Conjugation to Nanoemulsions. Data in Brief 2017, 15, 824–827. https://doi.org/10.1016/j.dib.2017.10.058

Diagnostic and Therapeutic Nuclear Medicine for Neuroendocrine Tumors; Pacak, K., Taïeb, D., Eds.; Springer International Publishing: Cham, 2017. https://doi.org/10.1007/978-3-319-46038-3

Kauss, T.; Marchivie, M.; Phoeung, T.; Gaubert, A.; Désiré, A.; Tonelli, G.; Boyer, C.; Langlois, M.-H.; Cartwright, A.; Gomes, M.; White, N.; Gaudin, K. Preformulation Studies of Ceftriaxone for Pediatric Non-Parenteral Administration as an Alternative to Existing Injectable Formulations. European Journal of Pharmaceutical Sciences 2017, 104, 382–392. https://doi.org/10.1016/j.ejps.2017.04.010

Jain, D.; Karajic, A.; Murawska, M.; Goudeau, B.; Bichon, S.; Gounel, S.; Mano, N.; Kuhn, A.; Barthélémy, P. Low-Molecular-Weight Hydrogels as New Supramolecular Materials for Bioelectrochemical Interfaces. ACS Applied Materials & Interfaces 2017, 9 (1), 1093–1098. https://doi.org/10.1021/acsami.6b12890

Ramin MA, Latxague L, Sindhu KR, Chassande O, Barthélémy P, (2017) “Low molecular weight hydrogels derived from urea based-bolaamphiphiles as new injectable biomaterials” Biomaterials doi: 10.1016/j.biomaterials.2017.08.034.

Prévot G, Kauss T, Lorenzato C, Gaubert A, Larivière M, Baillet J, Laroche-Traineau J, Jacobin-Valat MJ, Adumeau L, Mornet S, Barthélémy P, Duonor-Cérutti M, Clofent-Sanchez G, Crauste-Manciet S, (2017) “Iron oxide core oil-in-water nanoemulsion as tracer for atherosclerosis MPI and MRI imaging » International Journal of Pharmaceutics, in press.

Carla A. H. Prata, Nathanel R. Luman, Yuan Li, Dan Luo, Thomas J. McIntosh, Philippe Barthélémy, and Mark W. Grinstaff. (2017) “Synthesis of Cationic Amphiphilic Surface-Block Dendrimers.” Journal of Inorganic and Organometallic Polymers and Materials, DOI 10.1007/s10904-017-0651-4

Maisani M, Ziane S, Ehret C, Levesque L, Siadous R, Le Meins JF, Chevalier P, Barthélémy P, De Oliveira H, Amédée J, Mantovani D, Chassande O. (2017) A new composite hydrogel combining the biological properties of collagen with the mechanical properties of a supramolecular scaffold for bone tissue engineering. J Tissue Eng Regen Med. doi: 10.1002/term.2569.

A. Ramin, K. R. Sindhu, A. Appavoo, K. Oumzil, M. W. Grinstaff, O. Chassande, P. Barthélémy (2017) “Cation Tuning of Supramolecular Gel Properties: A New Paradigm for Sustained Drug Delivery” Adv. Mater. DOI: 10.1002/adma.201605227.

Karakia, S. Benizrie, R. Mejíasa, V. Baylota, N. Branger, T. Nguyen, B. Vialet, K. Oumzil, P. Barthélémy, P. Rocchi (2017) “Lipid-oligonucleotide conjugates improve cellular uptake and efficiency of TCTP-antisense in castration-resistant prostate cancer”, Journal of Controlled Release 258, 1–9

Latxague, A. Gaubert, D. Maleville, J. Baillet, M. Ramin, and P. Barthélémy (2016) “Carbamate based bolaamphiphile as Low Molecular Weight Hydrogelators”, Gels, 2, 25.

Vazquez, R.; Boubet, K.; Guerrault-Moro, M.-N.; Crauste-Manciet, S. Impact of Handling Errors for Chemical Cross-Contamination Risk for the Preparation of Parenteral Cytotoxic Drugs. Pharmaceutical Technology in Hospital Pharmacy 2016, 1 (3). https://doi.org/10.1515/pthp-2015-0009

Grélaud, S.; Desvergnes, V.; Landais, Y. Stereocontrolled (Me ₃ Si) ₃ SiH-Mediated Radical and Ionic Hydride Transfer in Synthesis of 2,3,5-Trisubstituted THF. Org. Lett. 2016, 18 (7), 1542–1545. https://doi.org/10.1021/acs.orglett.6b00303.

Jain, A. Karajic, M.Murawska, B. Goudeau, S. Bichon, S. Gounel, N. Mano, A. Kuhn, and P. Barthélémy (2016) “Low-Molecular-Weight Hydrogels as New Supramolecular Materials for Bioelectrochemical Interfaces” ACS Appl. Mater. Interfaces DOI: 10.1021/acsami.6b12890

Sybille Kenne, Ananda Appavoo, Jurgen Schulz, and Philippe Barthélémy (2016) “Nanoparticles for Radionuclide Imaging and Therapy: Principles” in Diagnostic and therapeutic nuclear medicine for neuroendocrine tumor, editors Karel Pacak and David Taïeb. Contemporary Endocrinology. ISBN 978-3-319-46036-9 ISBN 978-3-319-46038-3 (eBook)DOI 10.1007/978-3-319-46038-3

Ramin, J. Baillet, S. Benizri, L. Latxague, P. Barthélémy (2016) Uracile based Glycosyl-Nucleoside-lipids as low molecular weight organogelators, New Journal of chemistry, 40 (12)

Oumzil, M. A. Ramin, C. Lorenzato, A. Hemadou, J. Laroche, M. J. Jacobin-Valat, S. Mornet, C.-E. Roy, T. Kauss, K. Gaudin, G. Clofent-Sanchez, and P. Barthélémy (2016) “Solid Lipid Nanoparticles for Image-Guided Therapy of Atherosclerosis.” Bioconjugate Chemistry 27 (3), pp. 569-575

A. Kaplan, P. Barthélémy and M. W. Grinstaff, Chem. Commun., (2016), “Self-assembled nanofiber hydrogels for mechanoresponsive therapeutic anti-TNFα antibody delivery” 52, pp. 5860-5863

Oumzil, K. ; Tonelli, G. ; Benizri, S. ; Staedel, C. ; Chaffanet, M. ; Navailles L. ; and Barthélémy, P. (2015) “pH triggable Nucleolipids via hydrolysis of their orthoester polar head” ChemMedChem, 10 (11), pp. 1797-1801

Patwa A. ; Thiéry, A. ; Lombard, F. ; Lilley, MKS.; Boisset, C. ; Bramar, JF. ; Bottero JY. ; and Barthélémy, P. (2015), “Accumulation of nanoparticles in jellyfish mucus: a bio-inspired route to decontamination of nano-waste” Nature Scientific Reports, 5, 11387

Latxague, L., Ramin, M.A., Appavoo, A., Berto, P., Maisani, M., Ehret, C., Chassande, O., and Barthélémy, P. (2015) “Controlling stem cell behavior by fine tuning the supramolecular assemblies of Low Molecular Weight Gelators.” Angewandte Chemie, 54 (15), pp. 4517-4521.

Patwa A. ; Labille, J. ; Bottero JY. ; Thiéry, A. ; and Barthélémy, P. (2015) “Decontamination of nanoparticles from aqueous samples using low molecular weight gels.” Chem. Commun. 51 (13), pp. 2547-255m

Roy, C.-E., Kauss, T., Prevot, S., Barthélémy, P., and Gaudin, K. (2015) “Investigation of fatty acid analysis by hydrophilic interaction liquid chromatography and charged aerosol detector.” J. Chrom. A, doi: 10.1016/j.chroma.2015.01.046

Camplo, M., Raimundo, J.-M., Navailles, L., Grinstaff, M.W., Barthélémy, P. (2014) “Bioinspired systems in supramolecular chemistry and nanotechnology-introducing the SupraBio themed issue.” New J. Chem., Volume 38, Issue 11, 1 Pages 5120-5121.

Oumzil, K. ; Khiati, S. ; Camplo M. ; Koquely M. ; Chuttani, K. ; Chaturvedi S. ; Mishra, KM. ; and Barthélémy P. ; (2014) “Nucleolipids as building blocks for the synthesis of ^99mTc-labeled nanoparticles functionalized with folic acid.” New J. Chem., Volume 38, Issue 11, 1, Pages 5240-5246.

Patwa, A. ; Gissot, A. ; Oumzil, K. ; and Barthélémy P. (2014) “Lipid Oligonucleotide Bioconjugates: Applications in medicinal chemistry” in DNA in Supramolecular Chemistry and Nanotechnology, ed. E. Stulz and G. Clever, John Wiley & Sons Ltd., in print.

Barthélémy P. “Qu’est ce que le vivant; matières inanimées avez-vous donc une âme ?” in Elohi-Peuples indigènes et environnement, biannual review, PUB (Presse Universitaire de Bordeaux). (2014), vol 5/6, p 27-37.

Gissot, A. ; Oumzil, K. ; Patwa, A. ; and Barthélémy P. ; (2014) A hybrid lipid oligonucleotide: a versatile tool for supramolecular chemistry. New J. Chem., Volume 38, Issue 11, 1, Pages 5129-5134.

Thanassoulas, A.; Barthélémy, P.; Navailles, L.; Sigaud, G. (2014) From Nucleobases to Nucleolipids: An ITC Approach on the Thermodynamics of Their Interactions in Aqueous Solutions. Phys. Chem., 118(24):6570-85

Saez G., Aye M., De Meo M., Aimé A., Bestel I., Barthélémy P., Di Giorgio C. (2014) Genotoxic and oxidative responses in coelomocytes of Eisenia fetida and Hediste diversicolor exposed to lipid-coated CdSe/ZnS quantum dots and CdCl2. Environ Toxicol. doi: 10.1002/tox.21966.

Luvino, D. ; Khiati, S. ; Oumzil, K. ; Rocchi, P. ; Camplo, M. ; and Barthélémy P. (2013) Efficient delivery of therapeutic small nucleic acids to prostate cancer cells using ketal nucleoside lipid nanoparticles. J. Control. Release, 172, 954–961

Latxague L, Patwa A, Amigues E, Barthélémy P. (2013) Glycosyl-nucleolipids as new bioinspired amphiphiles. Molecules, 18(10):12241-63.

Patwa A, Salgado G, Dole F, Navailles L, Barthélémy P. (2013) Tuning molecular interactions in lipid-oligonucleotides assemblies via locked nucleic acid (LNA)-based lipids” Org. Biomol. Chem. 11(41):7108-12. doi: 10.1039/c3ob41707g.

Aimé A, Beztsinna N, Patwa A, Pokolenko A, Bestel I, Barthélémy P. (2013) Quantum Dot Lipid Oligonucleotide Bioconjugates: Toward a New Anti-MicroRNA Nanoplatform. Bioconjugate Chem., 24 (8), pp 1345–1355

Pokholenko, O., Gissot, A., Vialet, B., Bathany, K., Thiéry, A., and Barthélémy P. (2013) Lipid oligonucleotide conjugates as responsive nanomaterials for drug delivery. Mater. Chem. B, DOI: 10.1039/c3tb20357c.

Tonelli, G.; Oumzil, K.; Nallet, F.; Gaillard, C.; Navailles, L.; and Barthélémy P. (2013) Amino Acid–Nucleotide–Lipids: Effect of Amino Acid on the Self-Assembly Properties. Langmuir, 29 (18), pp 5547–5555.

Aye M, Di Giorgio C, Mekaouche M, Steinberg JG, Brerro-Saby C, Barthélémy P, De Méo M, Jammes Y. (2013) Genotoxicity of intraperitoneal injection of lipoamphiphile CdSe/ZnS quantum dots in rats. Mutat Res. 758(1-2):48-55. doi:pii: S1383-5718(13)00263-5.

Aye M, Di Giorgio C, Berque-Bestel I, Aime A, Pichon BP, Jammes Y, Barthélémy P, De Méo M. (2013) Genotoxic and mutagenic effects of lipid-coated CdSe/ZnS quantum dots. Mutat Res. 750(1-2):129-38.doi: 10.1016/j.

Taïb, N.; Aimé, A.; Moreau, L.; Camplo M.; Houmadi, S.; Desbat B.; Laguerre M.; Grinstaff, M.; Bestel I. and Barthélémy P. (2012) Formation of Supramolecular Systems via Directed Nucleoside-lipid Récognition. J. Colloid Interface Science, 1;377(1):122-30.

Lamanna, C.; Lusic, H.; Camplo, M.; McIntosh, T.; Barthélémy, P.; Grinstaff, M., (2012) Charge-reversal Lipids, Peptide-based Lipids, and Nucleoside-based Lipids for Gene Delivery. Accounts of Chemical Research, DOI: 10.1021/ar200228y

Desbat, B.; Arazam, N.; Khiati, S.; Tonelli, G.; Neri, W.; Barthélémy, P.; Navailles, L., (2012) Unexpected bilayer formation in Langmuir films of nucleolipids. Langmuir, 1;28(17):6816-25.

Taïb, N.; Aimé, A.; Houmadi, S.; Castano, S.; Barthélémy, P.; Laguerre, M.; Bestel, I.; (2012) Interactions of Nucleolipids with Oligonucleotides: molecular modelling and physicochemical studies. Langmuir, 15;28(19):7452-60.

Ziane S, Schlaubitz S, Miraux S, Patwa A, Lalande C, Bilem I, Lepreux S, Rousseau B, Le Meins JF, Latxague L, Barthélémy P, Chassande O. (2012) A thermosensitive low molecular weight hydrogel as scaffold for tissue engineering. Eur Cell Mater. 23;23: 147-60

Dolain, C., Patwa, A., Godeau, G., Barthélémy, P. (2012) “Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications.” Appl. Sci. 2, 245-259.

Latxague, L., Dalila, M.J., Patwa, A. Sophia, Z., Chassande, O., Godeau, G. and Barthélémy P. (2012) Glycoside nucleoside lipids (GNLs): An intrusion into the glycolipids’ world? C.R. Chimie, 15, 29–36

Thiéry, L. De Jong, J. Issartel, X. Moreau, G. Saez, P. Barthélémy, I. Bestel, C. Santaella, W. Achouak, M. Auffan, J. Rose and J-Y. Bottero (2012) Effects of metallic and metal oxide nanoparticles in aquatic and terrestrial food chains. Biomarkers responses in invertebrates and bacteria. Int. J. Nanotechnol., Vol. 9, No.3/4/5/6/7 pp. 181 – 203

Céballos, C., Khiati, S., Barthélémy, P. and Camplo M. (2012) Acyclic anionic nucleolipids for DNA delivery. Nanosci. Lett., 2: 20.

Latxague, L., Sophia, Z., Chassande, O., Patwa, A., L., Dalila, M.J., and Barthélémy P. (2011) Glycosylated nucleoside lipid promotes the liposome internalization in stem cells. Chem. Commun., 47, 12598–12600

Khiati, S., Luvino, D., Oumzil, K., Chauffert, B., Camplo, M. and Barthélémy P. (2011) Nucleoside Lipid-Based Nanoparticles for Cisplatin Delivery. ACS Nano, 5 (11), pp 8649–8655.

Patwa, A., Gissot, A., Bestel, I. and Barthélémy, P. (2011) Hybrid lipid oligonucleotide conjugates: synthesis, self-assemblies and biomedical applications. Chem. Soc. Reviews, 40, 5844–5854.

Zhang, X.-X., Prata, C., Berlin, A. J., McIntosh, T., Barthélémy, P. and Grinstaff, M. (2011) Synthesis, Characterization, and In Vitro Transfection Activity of Charge-Reversal Amphiphiles for DNA Delivery. Bioconjug. Chem., 22, 690–699.

Oumzil, K., Khiati, S., Grinstaff, M. W., and Barthélémy, P. (2011) Reduction-triggered delivery using nucleoside-lipid based carriers possessing a cleavable PEG coating. J. Control. Release, doi:10.1016/j.jconrel.2011.02.008

Zhang, X.X., Prata, C.A., McIntosh, T.J., Barthélémy, P., Grinstaff, M.W. (2010) The effect of charge-reversal amphiphile spacer composition on DNA and siRNA delivery. Bioconjug. Chem. 21, 988-993.

Godeau, G., Arnion, H., Brun, C., Staedel, C. and Barthélémy, P. (2010) Fluorocarbon oligonucleotide conjugates for nucleic acids delivery. Med. Chem. Commun., 1, 76–78

Saez, G., Moreau, X., De Jong, L., Thiéry, A., Dolain, C., Bestel, I., Di Giorgio, C., De Meo, M., Barthélémy, P. (2010) Development of new nano-tools: Towards an integrative approach to address the societal question of nanotechnology? Nano Today 5, 251-253.

Ceballos, C., Khiati, S., Prata, C.A., Zhang, X.X., Giorgio, S., Marsal, P., Grinstaff, M.W., Barthelemy, P., Camplo, M. (2010) Cationic nucleoside lipids derived from universal bases: A rational approach for siRNA transfection. Bioconjug. Chem. 21, 1062-1069.

Godeau, G., Brun C., Arnion, H., Staedel, C., Barthélémy, P. (2010) “Glycosyl-nucleoside fluorinated amphiphiles as components of nanostructured hydrogels” Tetrahedron Letters, (51), 1012-1015

Khiati, S., Pierre, N., Andriamanarivo, S., Grinstaff, M.W., Arazam, N., Nallet, F., Navailles, L., Barthélémy, P. (2009) Anionic nucleotide-lipids for in vitro DNA transfection. Bioconjug. Chem. (20), 1765-1772.

Godeau, G., Bernard, J., Staedel, C., Barthélémy, P. (2009) Glycosyl-nucleoside -lipid based supramolecular assembly as a nanostructured material with nucleic acid delivery capabilities. Chem. Commun., 5127-5129.

Barthélémy, P. (2009) Nucleoside-based lipids at work: From supramolecular assemblies to biological applications. Comptes Rendus Chimie 12, 171-179.

Godeau G. and Barthélémy P. (2009) Glycosyl-Nucleoside-Lipids as Low Molecular Weight Gelators. Langmuir, 25, 8447-8450.

Ceballos, C.; Prata, C. A. H.; Payet, D; Giorgio, S.; Garzino, F.; Barthélémy, P.; Grinstaff, M. W.; and Camplo, M. (2009) Cationic Nucleoside Lipids Based on a 3-Nitropyrrole Universal Base for siRNA Delivery. Bioconjug Chem, 20, 193-196.

Moreau, L.; Camplo, M.; Wathier, M.; Taib, N.; Laguerre, M.; Bestel, I.; Grinstaff, M. W.; Barthélémy, P., (2008) Real time imaging of supramolecular assembly formation via programmed nucleolipid recognition. J. Am. Chem. Soc., 130, (44), 14454-5.

Gissot, A.; Di Primo, C.; Bestel, I.; Giannone, G.; Chapuis, H.; Barthelemy, P., (2008) Sensitive liposomes encoded with oligonucleotide amphiphiles: a biocompatible switch. Chem. Commun., (43), 5550-2.

Godeau, G.; Staedel, C.; Barthélémy, P., (2008) Lipid-conjugated oligonucleotides via “click chemistry” efficiently inhibit hepatitis C virus translation. Journal of Medicinal Chemistry, 51, (15), 4374.

Chapuis, H., Bui, L., Bestel, I., Barthélémy, P., (2008) 2’-Lipid-modified oligonucleotides via a ‘Staudinger-Vilarrasa’ reaction. Tetrahedron Letters, 49, (48), 6838.

Gissot, A., Camplo, M., Grinstaff, M. W., Barthélémy, P., (2008) Nucleoside, nucleotide and oligonucleotide based amphiphiles: a successful marriage of nucleic acids with lipids. Org Biomol Chem, 6, (8), 1324-33.

De Jong, L.; Moreau, X.; Thiery, A.; Godeau, G.; Grinstaff, M. W.; Barthélémy, P., (2008) Amphiphilic copolymer for delivery of xenobiotics: in vivo studies in a freshwater invertebrate, a Mesostominae flatworm. Bioconjug Chem, 19, (4), 891-8.

Prata, C. A. H.; Li, Y.; Luo, D.; McIntosh, T. J.; Barthelemy, P.; Grinstaff, M. W., (2008) A new helper phospholipid for gene delivery. Chem. Commun., (13), 1566.

Prata, C. A.; Zhang, X. X.; Luo, D.; McIntosh, T. J.; Barthelemy, P.; Grinstaff, M. W., (2008) Lipophilic peptides for gene delivery. Bioconjug Chem, 19, (2), 418-20.

Bestel, I.; Campins, N.; Marchenko, A.; Fichou, D.; Grinstaff, M. W.; Barthelemy, P., (2008) Two-dimensional self-assembly and complementary base-pairing between amphiphile nucleotides on graphite. J. Colloid Interface Sci, 323, (2), 435-40.