Philippe Barthélémy
Professor, PhD, Director ChemBioPharm

Email

philippe.barthelemy@inserm.fr

Bio

Barthélémy received his doctorate in chemistry from the University of Montpellier II, France in 1993. He was then a postdoctoral fellow at Emory University in the group of Pr Fredric Menger (Lavoisier Grant and Emory Fellowship). In 1995 he was appointed as a temporary lecturer at the University of Avignon and as Associate Professor at the same University in 1996. P. Barthélémy worked also as a Visiting Associate Professor at Duke University in 2001. In 2005 he was appointed as full Professor at the University of Bordeaux Segalen (2010-2013). He has been Director of the ChemBioPharm team (http://chembiopharm.fr) and the Vice President of the University of Bordeaux Segalen (2011-2013). He is currently the Director of ARNA laboratory INSERM U1212/UMR CNRS 5320 (http://arna.cnrs.fr). Over the course of his tenure, Barthélémy’s research has yielded more than 150 peer-reviewed publications, more than 21 patents, and more than 100 oral invited conferences and oral presentations.

ORCID : https://orcid.org/0000-0003-3917-0579

Education

PhD. in Chemistry in July 1993, University of Montpellier II, France.

Habilitation à Diriger les Recherches, (HDR) December 2002.

Expertise

– Expert, European Research Council (ERC)

–  Expert, Agence d’Evaluation de la Recherche et de l’Enseignement Supérieur (AERES-HCERES)

– Expert ARO (Army Research Office, US Army), USA

– Expert NC3Rs, (National Centre for the Replacement, Refinement and Reduction of Animals in Research) London, UK.

– Reviewer for J. Am. Chem. Soc. (ACS), Langmuir (ACS), Organic Letters (ACS), J. Organic Chemistry (ACS), Macromolecules (ACS), Bioconjugate Chemistry (ACS), etc.

Awards

– IUPAC young observer (40th IUPAC Congress Beijing, China, August 2005).

– InnovaDay Future of Innovation prize 2010.

– Laureate “national Minstère/Oseo” Prize 2011 (Emergence).

– Laureate “concours national Tremplin” Entreprise/ESSEC 2011, Sénat.

Research grants

Since 2005, Philippe Barthélémy has received more than 20 grants (14 as PI/coordinator) for funding different projects, all related to molecular, supramolecular and nano-chemistry. These grants were obtained from the French National Agency of Research (ANR, EmergenceBio, PNANO), from other French government agencies, including ANSES, INSERM, INSERM transfert, SATT (AST) OSEO, ARC, Region Aquitaine, etc. and the ARO (Army Research Office, USA). Since 2005, these research programs have led to more than 80 publications and patents.

ANSES (Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail, NanoDeco, PI Barthélémy P., 2015-2018); Optoligo (INSERM transfert, PI Barthélémy P., 2014- 2018); US Army ARO (Suprabio V PI Barthélémy P. 2015-2016); ANR (ATHERANOS, CoPI, 2014-2017); ANR Emergence (Nanodecon, PI, 2012-2015); ANR (GelCell, 2010-2014, PI Barthélémy P.); ANR EmergenceBio, NANOVA, 2008 (PI Barthélémy P.); ANR PNANO, NANAN, 2008 (PI Barthélémy P.); ARO (US Army, USA, COAs 2006-2011, PI Barthélémy P.); Conseil Regional d’Aquitaine (CRAq) (Nanoparticles, PI Barthélémy P. 2008-2011); Région Aquitaine (LipNuc, PI L. Navailles, 2008-2009); Région Aquitaine (Pathinf, PI Behr C.); La Ligue; AFM (NADA); Internal call IFR66; etc.

5 recent publications

1. M. A. Ramin, K. R. Sindhu, A. Appavoo, K. Oumzil, M. W. Grinstaff, O. Chassande, P. Barthélémy, Mater. (2017) DOI: 10.1002/adma.201605227.
2. Oumzil, M. A. Ramin, C. Lorenzato, A. Hemadou, J. Laroche, M. J. Jacobin-Valat, S. Mornet, C.-E. Roy, T. Kauss, K. Gaudin, G. Clofent-Sanchez, and P. Barthélémy (2016) Bioconjugate Chemistry 27 (3), pp. 569-575.
3. Latxague, L., Ramin, M.A., Appavoo, A., Berto, P., Maisani, M., Ehret, C., Chassande, O., and Barthélémy, P. (2015) Angewandte Chemie, 54 (15), pp. 4517-4521.
4. Patwa A. ; Labille, J. ; Bottero JY. ; Thiéry, A.; and Barthélémy, P. (2015) Commun. 51 (13), pp. 2547-2550.
5. Khiati, S., Luvino, D., Oumzil, K., Chauffert, B., Camplo, M. and Barthélémy P. (2011) ACS Nano, 5 (11), pp 8649–8655.

5 recent patents

1. Barthélémy, P.; Gissot, A; Vialet, B. (2017) “«Tetramolecular parallel G-quadruplex-forming hydrophobically modified oligonucleotides»”. EP Patent EP17 305 651.6.
2. Barthélémy, P.; Oumzil K.; Clofent-Sanchez G.; Jacobin Valat, MJ.; Laroche; J.; Mornet S.; Gaudin K. (2015) “Lipid based nanovehicles loaded with nanoparticles and therapeutic agent for imaging guided therapy ”. EP Patent EP15305592.6
3. Barthélémy, P.; Oumzil K. (2015) “pH sensitive linkers”. EP Patent EP15305778.
4. Barthélémy, P.; Ramin M.; Latxague L.; Appavoo A.; Chassande O. Erhret C. “Glycosylated nucleobolaamphiphlile as new LMWG for biomedical applications. (2014) 6th Oct. : EP14290302.0
5. Barthélémy, P., Rocchi, P., Gissot, A., P. Oumzil, K., Acunzo, J., (2013) Hydrophobically modified antisense oligonucleotides comprising a triple alkyl chain. patent n° PCT/IB2013/001516.