Surname / Name: Aladin Hamoud, Ph.D student.
Thesis director : Dr. Valérie Desvergnes
Aladin Hamoud’s research is focused on the synthesis of original amphiphiles such as nucleolipids and glyco-nucleolipids. They showed a great ability to self-assemble thanks to various weak interactions and are of interest for the development of new biotechnologies. Some of them are already involved in the development of novel drug or biomolecule delivery systems.
A synthetic strategy based on the Stetter reaction was developed. It gives an access to many structures controlling the nature of the nucleoside, the lipid and also the linker between these two parts. Thereby the study of their physico-chemical properties will help us understanding the particular abilities of these compounds.
This work, funded by the French “Ministère de l’Enseignement Supérieur et de la Recherche”, was presented in three international congresses as poster or oral communication and received the award of the doctoral school of chemistry of Bordeaux in 2017.
Since 2015 – PhD student in organic chemistry, University of Bordeaux, France
2015 – Master degree in organic chemistry, University of Bordeaux, France
2012 – Bachelor degree in chemistry, University of Bordeaux, France
Internship and work experiences.
2015 Training period within Organic Synthesis and Natural Products ISM, Talence, France
5 months Supervision: Pr. Yannick Landais
Study of the reactivity of silylium cations, multi-step synthesis.
2014 Training period within Synthesis & Activity of Natural Substances, IECB, Pessac, France
2 months Supervision: Dr. Philippe Peixoto
Synthesis of spirolactones using hypervalent iodide, multi-step synthesis
2013 Training period within NSysA ISM, ENSCBP, Pessac, France
2 months Supervision: Dr. Stephane Arbault
Formation of liposomes for the development of cell-like systems, enzymatic chemistry
– Award from the doctoral school of chemistry of Bordeaux, 2017